Innovasis Announces Launch of Endeavor™ Stand-Alone Cervical IBF System featuring Beta+™ PEEK material
Innovasis Introduces Beta+™ HA/ß-TCP PEEK Technology Engineered to Actively Contribute to the Fusion Environment
SALT LAKE CITY, UT — March 3, 2026 — Innovasis announces the launch of the Endeavor™ Stand-Alone Cervical IBF System, engineered with proprietary Beta+™ technology — a bioactive composite integrating Hydroxyapatite (HA) and ß-Tricalcium Phosphate (ß-TCP) directly within a PEEK matrix.
While traditional PEEK implants provide structural support, they remain biologically inert. Beta+™ was developed to address that limitation.
By incorporating two distinct calcium phosphate phases into the implant body itself, Endeavor™ is designed to create a biologically responsive implant surface — one that supports osteoconductive activity and promotes a favorable cellular environment at the bone–implant interface.
Unlike surface coatings or sprayed applications, the HA and ß-TCP components in Beta+™ are integrated throughout the PEEK structure, enabling exposure at the implant surface and contributing to:
Osteoconductive Hydroxyapatite material properties distributed throughout PEEK
High resorption rate and ionic release profile of β-Tricalcium Phosphate (β-TCP)¹
Enhanced cellular responses1,2 and proliferation potential1,3
A surface environment designed to support new bone formation
“Material composition matters in fusion,” said Gary Rosenburg, MD. “With HA and ß-TCP integrated directly into the PEEK matrix, Endeavor™ represents a shift from passive structural devices to implants engineered to biologically participate in the fusion response.”
1. Jeong et al., Bioactive calcium phosphate materials and applications in bone regeneration. Biomaterials Research (2019) 23:4
Litak et al., Hydroxyapatite Use in Spine Surgery—Molecular and Clinical Aspect. Materials 2022, 15, 2906.
2. Liu et al., b-TCP Composites in Orthopaedics. Orthopaedic Surgery. Volume 4 · Number 3 · August, 2012
Litak et al., Hydroxyapatite Use in Spine Surgery—Molecular and Clinical Aspect. Materials 2022, 15, 2906.
3. Jeong et al., Bioactive calcium phosphate materials and applications in bone regeneration. Biomaterials Research (2019) 23:4
Evonik, Product Overview Vestakeep Fusion, https://medical.evonik.com/en/materials-and-solutions/vestakeep-peek/vestakeep-fusion
The Science Behind Beta+™
Beta+™ leverages the complementary biological roles of two calcium phosphates:
Hydroxyapatite (HA)
Provides long-term osteoconductive structure and surface characteristics known to support bone apposition.
ß-Tricalcium Phosphate (ß-TCP)
Resorbs over time and releases calcium and phosphate ions — elements recognized for their role in osteoprecursor cell signaling and bone regeneration pathways.
The integration of these materials within the implant matrix is designed to create a microenvironment conducive to bone ongrowth and biological fixation — while maintaining the modulus characteristics and radiolucency advantages associated with PEEK.
Engineered for Stability. Designed for Biology.
The Endeavor™ Stand-Alone Cervical IBF System combines Beta+™ biomaterial science with a fixation platform designed for stability and surgical efficiency:
Bi-convex Beta+™ PEEK implant body
Integrated titanium faceplate
Variable-angle and fixed-angle fixation screws
Pyramidal anti-expulsion teeth
Radiographic markers for visualization
One-step locking cover plate
Available in multiple footprints and lordotic options, the system is indicated for anterior cervical interbody fusion procedures in skeletally mature patients with degenerative disc disease from C2–T1.
A Material-Driven Philosophy
Endeavor™ reflects Innovasis’ broader commitment to bioactive implant design — focusing not only on mechanical performance, but on the biological interface between implant and host bone.
“Innovasis believes the next generation of spinal implants will be defined by material science,” said Matt Stuttle, President and CEO. “Beta+™ is designed to move beyond passive support and toward biologically engaged fusion platforms.”
Customer-Centric Approach
Innovasis places a strong emphasis on understanding the needs of both healthcare providers and patients. This customer-centric approach drives the company's efforts to provide cost-effective solutions without sacrificing quality. By listening to feedback and continuously improving products and services, Innovasis ensures it meets the evolving needs of the market.
Additionally, Innovasis offers comprehensive support to healthcare providers, including training and educational resources. This ensures that providers are well-equipped to use Innovasis products effectively, leading to the opportunity for better patient outcomes and greater satisfaction.
About Innovasis
Innovasis is a research-driven spinal implant company focused on the development of advanced spinal technologies and enhanced bioactive materials engineered to improve clinical outcomes.
Innovasis
614 East 3900 South
Salt Lake City, UT 84107
801.261.2236
www.innovasis.com