HANANO SURFACE®

HAnano Surface is a registered trademark of Promimic AB, Mölndal, Sweden

EXCELERATE

HAnano Surface® combines several properties, known to improve osseointegration, in one unique surface modification. 4

HAnano Surface® is a 20 nanometer thin implant surface modification composed of crystalline hydroxyapatite (HA) particles that through shape, composition, and structure mimic human bone tissue. HAnano Surface® is used clinically and has proven to significantly accelerate and enhance osseointegration of implants.*

REFERENCES

HAnano Surface is a registered trademark of Promimic AB, Mölndal, Sweden

4 https://www.promimic.com/products-and-technology/

*osseointegration of human dental implants

Promote Bony Ongrowth

Significantly accelerate and enhance integration of implants using nano-sized crystalline hydroxyapatite particles*

Hydrophilic properties improve adsorption of blood and extracellular fluids, promoting an osteoconductive integration process

Enables newly-formed bone to grow directly into the micrometer topography (roughness) of the implant surface

In laboratory studies using animals, HAnano showed early bone formation and improved implant anchoring*

REFERENCES

Meirelles L (2008), ‘The effect of Chemical and Nanotopographical Modification on the early stages of osseointegration’

Jimbo R (2011), ‘Histological and three-dimensional evaluation of osseointegration’

Jimbo R (2012), ‘Nano hydroxyapatite-coated implants improve bone nanomechanical properties’.

*in laboratory studies using animals

Wettability/Hydrophilicity

AxTiHA Integrated with HAnano Surface® *real time

HAnano Surface® Remains Hydrophilic Over Time

Acid etched titanium implants were lowered into dyed water (down to a predetermined length).
Evaluation of liquid absorption after 0, 1, 4, 8 and 12 weeks of storing in glass vials with a Teflon gasket.
Results
HAnano Surface® coated implants remain hydrophilic over time.
Heat treated implants become more hydrophobic over time.